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Robert Smith

Department of Biological Sciences

Education

  • MS, Pharmacognosy, Philadelphia College of Pharmacy & Science (1973)
  • BS, Biology, Philadelphia College of Pharmacy & Science (1970)

Faculty Appointments

Distinguished Assistant Professor of Biology

Research Interest

Plant tissue culture as a means of secondary metabolite production
Development of effective screening procedures for antihelminthic testing of crude plant extracts

Synopsis

Plant tissue culture as a means of secondary metabolite production. Current projects include promotion and evaluation of taxane production in

Taxus media cv Hicksii. I also work on developing models for organogenesis and embryogenesis in plant tissue culture. A new focus is development of effective screening procedures for antihelminthic testing of crude plant extracts using Caenorhabditis elegans as the test organism.

Publications & Presentations

  • Waterman, C., Smith, R.A., Pontiggia, L., and DerMarderosian, A. Anthelmintic screening of Sub-Saharan African plants used in traditional medicine. Journal of Ethnopharmacology. (accepted November 24, 2009).

  • Smith, R. A., Pontiggia, L., Waterman, C., Lichtenwalner, M., Wasserman, J. 2009. Comparison of motility, recovery, and methyl-thiazolyl-tetrazolium reduction assays for use in screening plant products for anthelmintic activity. Parasitology Research 105: 1339-1343.
  • Smith, R. A., G. Burns, B. Freud, S. Fenning, R. Hoffman and Sabapathi, D. 2000. Demonstrating type I and type II errors using Rhizopus spore diameter data. The American Biology Teacher, 62:654–657.
  • Smith, R. A., Drummond, S, Haines, A., Porter, J. and Hock, R. 2001. Induction of umbelliferone in sweet potato cell suspension culture using mercuric chloride. Biotechnology Letters, 23:1397–1400.
  • Nguyen, T., Eshragi, J., Gonyea, G., Ream, R. M. and Smith, R. A. 2001. Studies on factors influencing stability and recovery of paclitaxel from suspension media and cultures of Taxus cuspidata cv Densiformis by high-performance liquid chromatography. Journal of Chromatography A., 911:55-61.
  • Smith, R. A. and Belzer, N. 2002. Production of haploid tobacco plants using anther culture. The American Biology Teacher, 6:443–448.
  • Smith, R. A., Calviello, C., DerMarderosian, A and Palmer, M. E. 2000. "Evaluation of antibacterial activity of Belizean plants: An improved method." Pharmaceutical Biology, 38: 25-29

Contact Information

Office:

Science and Technology Center
Room # 275
Box # 38

Phone: 215.596.8918

Email: r.smith@usp.edu


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